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Issaquena County, Mississippi Map

Explore Issaquena County, Mississippi with this interactive street and satellite map. Browse all 3 cities and towns in Issaquena County below.

Interactive Map of Issaquena County, Mississippi

CountyIssaquena
StateMississippi (MS)
County SeatMayersville
CountryUnited States of America
Latitude32.845037
Longitude-90.958159
Cities & Towns3
Area Codes601, 662

About Issaquena County, Mississippi

Issaquena County occupies a singular expanse of the Mississippi Delta, defined by the relentless, flat horizon where the sky seems to press down with a heavy, humid weight. To the west, the Mississippi River serves as a shifting, liquid border, its currents carving the silt-heavy earth into a landscape of oxbow lakes and dense, tangled bottomland forests. The terrain here possesses a stark, primordial quality, marked by low-lying basins that hold the winter rains long after the sun has begun to bake the fields into a cracked, gray mosaic. In the late afternoon, the light takes on a bruised, golden hue that catches the dust rising from the levees, turning the air into a shimmering veil that obscures the boundary between the water and the shore.

Issaquena County emerged from the wilderness during the mid-nineteenth century, carved from the vast, timbered tracts that once stood as an impenetrable barrier to settlement. Its administrative center drifted across the landscape in its early years, compelled by the volatile nature of the river and the shifting needs of a frontier society until it eventually settled into a permanent, quiet existence. The people who first broke this ground contended with the formidable task of clearing cypress brakes and managing the unpredictable floods that regularly reshaped the map. Today, the remnants of that era persist in the deep, slow quiet of the backroads, where the silence is broken only by the sudden, sharp call of a hawk or the distant, rhythmic hum of agricultural machinery working the heavy, dark soil.

Agriculture dictates the pulse of life in Issaquena County, as fields of soybeans and cotton stretch toward the river in a geometry of green and white. The economy remains tethered to the fertility of the alluvial plain, requiring a persistent, stoic labor that reflects the character of those who remain in this isolated corridor. Life here is measured not by the clock, but by the cycle of the seasons and the rising or falling of the river, which dictates the accessibility of the wild, overgrown corridors of the levee districts. In the evenings, when the humidity relents and the shadows stretch long across the furrows, there is a profound sense of solitude that settles over the land, a stillness that feels as old and enduring as the river itself.

Cities and Towns in Issaquena County

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About This Issaquena County Map Page

This page provides an interactive map of Issaquena County, Mississippi alongside links to detailed street maps for 3 cities and towns. The county seat is Mayersville. Each city and town map page includes live weather, local news and precise GPS coordinates.

The Search Maps button below the county map opens USGS topographic maps and aerial imagery as base layers, with a labelled U.S. National Grid (USNG) overlay, a distance and bearing tool, and a single-fix GPS readout giving your USNG grid reference and latitude and longitude.

Location data is sourced from the USGS GNIS database and verified by coordinates, not name matching alone.

Page generatedSeptember 2026
Location dataUSGS GNIS database; coordinates matched to 2020 US Census records