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| City | Perryville |
| State | Missouri (MO) |
| County | Perry |
| Country | United States of America |
| Timezone | Central Time (America/Chicago) |
| Latitude | 37.72422 |
| Longitude | -89.86122 |
| Population | 8,536 |
| Density | 403.6 /km² |
| Incorporated | N/A |
| ZIP Code(s) | 63775 |
| Area Code | 816 |
| County Seat | Perryville |
| School District | Perry County 32 School District |
Perryville is a locality in Perry County, Missouri, United States. It has a population of approximately 8,536. The population density is 403.6 people per km². Perryville is located at 37.7242°N, 89.8612°W. It observes the Central Time (America/Chicago) timezone. ZIP code: 63775.
Perryville rests in a gentle cradle of rolling hills, the land here breathing with a subtle, persistent life. It lies 34.5 miles north-north-west of Cape Girardeau, MO (from Cape Girardeau, MO: bearing 327°T), and is situated 2.4 miles north-north-east of Shakertowne. The sky above often wears a soft, hazy mantle, particularly as the sun begins its slow descent, painting the western horizon in muted golds and bruised purples that reflect off the broad, slow-moving Mississippi River not far to the east. This is a place where the earth feels solid beneath your feet, a deep, rich loam that has cradled farms and homesteads for generations. The air, especially after a summer rain, carries the scent of damp earth and the sweet, heavy perfume of honeysuckle that clings to old fences and spills over weathered barns. The landscape itself seems to hold a quiet, unhurried dignity, a testament to the enduring spirit of the land and those who have worked it. The history of Perryville is deeply entwined with the fertile grounds and the river's generous, sometimes tempestuous, nature. Originally settled by German immigrants seeking religious freedom and fertile soil, Perryville retains a strong connection to its European heritage, evident in the enduring traditions and the sturdy, well-maintained architecture. The local economy, once heavily reliant on agriculture and the timber industry, has diversified, with manufacturing and small businesses contributing to the town's steady pulse. The presence of the National Cemetery, a solemn reminder of past conflicts, stands as a poignant landmark, drawing visitors and offering a quiet space for reflection. Perryville’s character is one of quiet resilience, a place where hard work is valued, and the community’s roots run deep, drawing strength from both the land and its layered past.
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This page provides an embedded street and satellite map of Perryville, Missouri — switch between views using the small square in the bottom left-hand corner of the map. Coordinates: 37.72422, -89.86122. Live weather conditions are sourced directly from the National Weather Service, with current observations and a 7-day forecast also powered by Open-Meteo. Real-time local news and world news feeds keep the page current, while a Wikipedia summary or an editorially written description provides background on Perryville and Perry County.
Detailed location data for Perryville includes the ZIP code (63775), telephone area code (816), county seat of Perry County (Perryville), and school district assignment (Perry County 32 School District). These are among the most commonly searched location details for any US city or town.
Location data is drawn from the USGS Geographic Names Information System (GNIS) and cross-verified against 2020 US Census records by coordinate proximity — ensuring the correct Perryville is identified even where the name is shared across multiple counties or states. Population figures are sourced from the 2020 US Census.
| Page generated | July 2026 |
| Location data | SimpleMaps US Cities Database; coordinates matched to USGS GNIS definitive data |
| Wikipedia validation | Article content matched to USGS GNIS coordinates via Wikipedia geosearch API. Location verified by proximity — not name matching alone. |