Perryville, Missouri — live current conditions, hourly and 7-day forecasts, NWS alerts, aviation weather, radar and satellite imagery for Perryville, Perry County.
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Perryville rests in a gentle cradle of rolling hills, the land here breathing with a subtle, persistent life. It lies 34.5 miles north-north-west of Cape Girardeau, MO (from Cape Girardeau, MO: bearing 327°T), and is situated 2.4 miles north-north-east of Shakertowne. The sky above often wears a soft, hazy mantle, particularly as the sun begins its slow descent, painting the western horizon in muted golds and bruised purples that reflect off the broad, slow-moving Mississippi River not far to the east. This is a place where the earth feels solid beneath your feet, a deep, rich loam that has cradled farms and homesteads for generations. The air, especially after a summer rain, carries the scent of damp earth and the sweet, heavy perfume of honeysuckle that clings to old fences and spills over weathered barns. The landscape itself seems to hold a quiet, unhurried dignity, a testament to the enduring spirit of the land and those who have worked it. The history of Perryville is deeply entwined with the fertile grounds and the river's generous, sometimes tempestuous, nature. Originally settled by German immigrants seeking religious freedom and fertile soil, Perryville retains a strong connection to its European heritage, evident in the enduring traditions and the sturdy, well-maintained architecture. The local economy, once heavily reliant on agriculture and the timber industry, has diversified, with manufacturing and small businesses contributing to the town's steady pulse. The presence of the National Cemetery, a solemn reminder of past conflicts, stands as a poignant landmark, drawing visitors and offering a quiet space for reflection. Perryville’s character is one of quiet resilience, a place where hard work is valued, and the community’s roots run deep, drawing strength from both the land and its layered past.
| Location | Perryville, Perry County, Missouri |
| Coordinates | 37.72422°N, 89.86122°W |
| Timezone | Central Time (America/Chicago) |
| ZIP Code(s) | 63775 |
| Area Code | 816 |
| Page generated | June 2026 |
| Weather data | Open-Meteo (open-source), NOAA National Weather Service |